2004-2010

Gesamtpublikationsliste des Instituts 2004-2010

2004

S.R. Thurau, T.R. Mempel, A. Flügel, M. Dietrichs-Möhring, F. Krombach, N. Kawakami, G. Wildner. The fate of autoreactive, GFP+ T cells in rat models of uveitis analyzed by intravital fluorescence microscopy and FACS. International Immunology 16 (2004):1573-82.

F.X. Weilbach, A. Chan, K.V. Toyka, R. Gold. The cardioprotector dexrazoxane augments therapeutic efficacy of mitoxantrone in EAE . Clinical and Experimental Immunology 135 (2004):49-55

L. Visan, I.A. Visan, A. Weishaupt, H.H. Hofstetter, K.V.Toyka, T. Hünig, R. Gold. Tolerance induction by intrathymic expression of myelin P0 protein. Journal of Immunology 172 (2004):1364-70

G. Stoll, C. Wesemeier, R. Gold , L. Solymosi, K.V. Toyka, M. Bendszus. In-vivo monitoring of macrophage infiltration in experimental autoimmune neuritis by magnetic resonance imaging. Journal of Neuroimmunology 149 (2004):142-6.

N. Kawakami, S. Lassmann, Z. Li, F. Odoardi, T. Ritter, T. Ziemssen, W.E.F. Klinkert, J.W. Ellwart, M. Bradl, K. Krivacic, H. Lassmann, R.M. Ransohoff, H-D. Volk, H. Wekerle, C. Linington, A. Flügel. The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis. Journal of Experimental Medicine 199 (2004): 185-197.

A.Weishaupt, M. Kreiss, R.Gold, T. Herrmann. Modulation of experimental autoimmune encephalomyelitis by administration of cells expressing antigenic peptide covalently linked to MHC class II. Journal of Neuroimmunology 152 (2004):11-19

A. Wellmer, M.v. Mering1, A. Spreer, R. Diem, H. Eiffert, C. Noeske, S. Bunkowski, R.Gold, R. Nau. Experimental Pneumococcal Meningitis: Impaired Clearance of Bacteria from the Blood in Bcl-2-deficient Mice due to Increased Apoptosis in the Spleen. Infection and Immunity 72 (2004):3113-19

R.A. Linker, R. Gold. MBP-induced EAE in C57BL/6 mice. Journal of Immunology 173 (2004):2896 (letter)

F. Aboul-Enein, J. Bauer, M. Klein,A. Schubart, A. Flügel, T. Ritter, N. Kawakami, F. Siedler, C. Linington, H. Wekerle, H. Lassmann, M. Bradl. Selective and Antigen dependent effects of myelin degeneration on Central Nervous System inflammation. Journal of Neuropathology and Experimental Neurology 63 (2004): 1284-96.

P. Ströbel, A. Bauer, B. Puppe, T. Kraushaar, A. Krein, K. Toyka, R. Gold, M. Semik, R. Kiefer, W. Nix, B. Schalke, H. K. Müller-hermelink, A. Marx. Tumor Recurrence and Survival in Patients Treated for Thymomas and Thymic Squamous Cell Carcinomas: A Retrospective Analysis. Journal of Clinical Oncology 22 (2004):1501-9

K. Ruprecht, E. Klinker, T. Dintelmann, P. Rieckmann, R. Gold. Plasma Exchange in the Treatment of Severe Optic Neuritis: Analysis of a Series of 10 Patients Neurology 63 (2004): 1081-1083

Schmidt J, Rakocevic G, Raju R, Dalakas MC. Inducible Costimulator and ICOS-Ligand in IBM Muscle: Significance for CD8+ T cell Cytotoxicity. Brain 127 (2004): 1182-90.

 

2005

M. Bradl, J. Bauer, A. Flügel, H. Wekerle and H. Lassmann. Complementary contribution of CD4 and CD8 T lymphocytes to T-cell infiltration of the intact and the degenerative spinal cord. American Journal of Pathology, 166 (2005): 1441-50.

A. Chan, F.X. Weilbach, K.V. Toyka, R. Gold. Mitoxantrone induces delayed cell death in peripheral blood leukocytes of multiple sclerosis patients: an ex vivo study Clinical and Experimental Immunology 139 (2005): 152-158

N. Kawakami, U.V. Nägerl, F. Odoardi, T. Bonhoeffer, H. Wekerle, A. Flügel. Live imaging of effector cell trafficking and autoantigen recognition within the unfolding autoimmune encephalomyelitis lesion. Journal of Experimental Medicine, 201 (2005): 1805-14.

R. Gold, P. Rieckmann, P. Chang and J. Abdalla for the PRISMS Study Group. The long-term safety and tolerability of high-dose interferon b-1a in relapsing-remitting multiple sclerosis: 4-year data from the PRISMS study European Journal of Neurology 12 (2005): 649-656

C. Sommer, A. Weishaupt, J. Brinkhoff, L. Biko, C. Wessig, R. Gold, KV Toyka. Paraneoplastic stiff-person syndrome: Passive transfer to the rat with IgG antibodies to amphiphysin Lancet 365 (2005): 1406-1411

M I Leite, P Stroebel, M Jones, K Micklem, R Moritz, R Gold, BCG Schalke, S Berrih-Aknin, J Newsom-Davis, E Niks, A Canelhas, F Scaravilli, A Marx , N Willcox and A Vincent. Lack of thymic abnormalities in MuSK antibody-positive MG patients: a morphometric comparison. Annals of Neurology 57 (2005): 444-448

N. Kawakami, F. Odoardi, T. Ziemssen, M. Bradl, T. Ritter, O. Neuhaus, H. Lassmann, H. Wekerle, A. Flügel. Autoimmune CD4+ T cell memory: Life long persistence of encephalitogenic T cell clones in healthy immune repertoires. Journal of Immunology, 175 (2005):69-81.
R.A. Linker, E. Rott, H.H. Hofstetter, T. Hanke, K.V. Toyka, R. Gold. EAE in beta-2 microglobulin deficient mice: axonal damage can occur in absence of demyelination and MHC-I restricted immune responses Neurobiology of Disease 19 (2005): 218-228

I. Uttner, S. Müller, C. Zinser, M. Maier, S. Süßmuth, A. Claus, B. Ostermann, E. Elitok, D. Ecker, J. Brettschneider, R. Gold, H. Tumani. Pulsed methylprednisolone therapy induces reversible impairment of memory in patients with MS. Neurology 64 (2005): 1971-1973

S. Vogler, R. Goedde , B. Miterski, R. Gold, A. Kroner, U.K. Zettl, P. Rieckmann, J.T. Epplen, S.M. Ibrahim. Association of a common polymorphism in the promoter of UCP2 with susceptibility to multiple sclerosis. Journal of Molecular Medicine 83 (2005): 806-11

M. Reinhardt, P. Hauff, R.A. Linker, A. Briel, R. Gold, P. Rieckmann, G. Becker, K.V. Toyka, M. Mäurer, M. Schirner. Sensitive particle acoustical quantification provides imaging and quantification of cell adhesion molecules in EAE. Neuroimage 15 (2005): 267-278

N. Beyersdorf, S. Gaupp, K. Balbach, J. Schmidt, K.V. Toyka, C.H., T. Hanke, T. Hünig, T. Kerkau, R. Gold. Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis. Journal of Experimental Medicine 202 (2005): 445-455.

 

2006

R.A. Linker, A. Mohr, L. Cepek, R. Gold and H. Prange.Core hypothermia in multiple sclerosis. Case report with MRI localization of a thalamic lesion. Multiple Sclerosis 12 (2006) 112-115

Y. Cao, C. Toben, S.Y. Na, K. Stark, L. Nitschke, A. Peterson, R. Gold, A. Schimpl, T.Hünig. Induction of experimental autoimmune encephalomyelitis in transgenic mice expressing ovalbumin in oligodendrocytes . European Journal of Immunology 36 (2006): 207-15

H. Hofstetter, K.V. Toyka, R. Gold. Permanent effector phenotype of neuroantigen-specific T cells acquired in the central nervous system during experimental allergic encephalomyelitis.
Neuroscience Letters 391 (2006): 127-30

H. Voigt, D. Schrama, A. O. Eggert, C. S. Vetter, K. Müller-Blech, M. H. Andersen, J. C. Becker, F. Lühder: CD28-mediated costimulation impacts on differentiation of DC-vaccination induced T cell responses. Clinical Experimental of Immunology. 143 (2006), 93-102

T. Kirchberger, G. Wagner, J. Xu, C. Cordiglieri, P. Wang, A. Gasser, R. Fliegert, S. Bruhn, A. Flügel, F.E. Lund, L. Zhang, B.V.L. Potter, A.H. Guse. Cellular effects and metabolic stability of N1-cyclic inosine diphosphoribose and its derivatives. British Journal of Pharmacology 149 (2006): 337-44.

D. Schrama, P. Terheyden, K. Otto, U. Kammerer, E.B. Brocker, F. Lühder, D. Cosman, M.H. Andersen, J.C. Becker. Expression of the NKG2D ligand UL16 binding protein-1 (ULBP-1) on dendritic cells. European Journal of Immunology. 36 (2006), 65-72.

K.M. Dennehy, F. Elias, G. Zeder-Lutz, X. Ding, D. Altschuh, F. Lühder, T. Hünig. Monovalency of CD28 maintains the antigen dependence of T cell costimulatory responses. Journal of Immunology. 176 (2006), 5725-5729

S. Schilling, S. Goelz, R. Linker, F. Lühder,R.Gold. Fumaric acid esters are effective in chronic EAE and suppress macrophage infiltration. Clinical Experimental of Immunology. 145 (2006), 101-107

H. Hofstetter, F. Lühder, K.V. Toyka, R. Gold. IL-17 production by thymocytes upon CD3 stimulation and costimulation with microbial factors. Cytokine 34 (2006), 184-197

H. Reichardt, R. Gold, F. Lühder:Mechanisms of glucocorticoid action in the control of Multiple Sclerosis and its animal model Experimental Autoimmune Encephalomyelitis.
Expert Reviews of Neurotherapeutics 6 (2006), 1657-70.

 

2007

N. Kruse, S. Cetin, A. Chan, R. Gold, F. Lühder. Differential expression of BDNF mRNA splice variants in mouse brain and immune cells. Journal of Neuroimmunology 182 (2007), 13-21. [Pubmed]

F. Odoardi, N. Kawakami, W.E.F. Klinkert, H. Wekerle, A. Flügel. Blood-born soluble protein antigen intensifies T cell activation in autoimmune CNS lesions and exacerbates clinical disease. Proceedings of the National Academy of Sciences of the United States of America 104 (2007): 18625-18630. [Pubmed]

R. Grundtner, K. Dornmair, R. Dahm, A. Flügel, N. Kawakami, M. Zeitelhofer, L. Schoderboeck, M. Nosov, E. Selzer, M. Willheim, M. Kiebler, H. Wekerle, H. Lassmann, M. Bradl. Transition from enhanced T cell infiltration to inflammation in the myelin-degenerative central nervous system. Neurobiology of Disease 28 (2007):261-75. [Pubmed]

F. Odoardi, N. Kawakami, Z. Li, C. Cordiglieri, K. Streyl, M. Nosov, W.E.F. Klinkert, J.W. Ellwart, J. Bauer, H. Lassmann, H. Wekerle, A. Flügel. Instant effect of soluble autoantigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America 16 (2007): 920-25. [Pubmed]

K. M. Dennehy, F. Elias, K.D. Fischer, T. Hünig and F. Lühder: Mitogenic CD28 signals utilise the exchange factor Vav1 to amplify TCR signalling at the SLP-76 signalosome. Journal of Immunology 178 (2007), 1363-1371. [Pubmed]

J.v.d. Brandt, F. Lühder, K.G. McPherson, K.L. de Graaf, D. Tischner, S. Wiehr, T. Herrmann, R. Weissert, R. Gold, H.M. Reichardt. Enhanced glucocorticoid receptor signalling in T cells impacts on thymocyte apoptosis and adaptive immune responses. American Journal of Pathology 170 (2007), 1041-53. [Pubmed]

F. Lühder, R. Gold: Many roads lead to Rome: Heterogeneity among encephalitogenic T cell clones. Journal of Neuroimmunology 192 (2007), 1-2. [Pubmed]

R. Cassiani-Ingoni, P.A. Muraro, T. Magnus, S. Reichert-Scrivner, J. Schmidt, J. Huh, J.A. Quandt, A. Bratincsak, T. Shahar, F. Eusebi, L.S. Sherman, M.P. Mattson, R. Martin, M.S. Roa. Disease progression after bone marrow transplantation in a model of multiple sclerosis is associated with chronic microglial and glial progenitor response. Journal Neuropathology Experimental Neurology 66 (2007): 637-649. [Pubmed]

J.D. Lunemann, J. Schmidt, D. Schmid, K. Barthel, A. Wrede, M.C. Dalakas, C. Münz. β-amyloid is a Substrate of Macroautophagy in Sporadic Inclusion Body Mysositis. Annals of Neurology 61 (2007): 476-483. [Pubmed]

J.D. Lunemann, J. Schmidt, M.C. Dalakas, C. Munz. Macroautophagy as a pathomechanism in sporadic inclusion body myositis. Autophagy 3 (2007): 384-386. [Pubmed]

N. Gong, U. Pleyer, K. Vogt, I. Anegon, A. Flügel, H.-D. Volk, T Ritter. Local over-expression of nerve growth factor in corneal transplants improves allograft survival. Investigative Ophthalmology & Visual Science 48 (2007):1043-1052. [Pubmed]

M. Salajegheh, R. Raju, J. Schmidt, M.C. Dalakas. Upregulation of Thrombospondin-1 (TSP-1) and its binding partners, CD36 and CD47, in sporadic inclusion body myositis. Journal of Neuroimmunology 187 (2007):166-174. [Pubmed]

H. Gelderblom, J. Schmidt, D. Londoño, Y. Bai, J. Quandt, R. Hornung, A. Marques, R. Martin, D. Cadavid. Role of Interleukin 10 during Persistent Infection with the Relapsing Fever Spirochete Borrelia turicatae. American Journal of Pathology 170 (2007): 251-262. [Pubmed]

 

2008

R. Gold, F. Lühder: Interleukin-17: Extended Features of a Key Player in Multiple Sclerosis. American Journal of Pathology 172 (2008), 8-10. [Pubmed]

K.M. Rostasy, J. Schmidt, E. Bahn, T. Pfander, M. Piepkorn, E. Wilichowski, W.J. Schulz-Schaeffer. Distinct inflammatory properties of late-activated macrophages in inflammatory myopathies. Acta Myologica 27 (2008): 49-53. [Pubmed]

J. Schmidt and M.C. Dalakas: Inflammation interrelates to APP in sIBM: IL-1beta induces accumulation of beta-amyloid. Brain 2008; (letter, available online only, doi:10.1093/brain/awn164). [Brain]

J. Schmidt, K. Barthel, A. Wrede, M. Salajegheh, M. Bähr, M.C. Dalakas. Interrelation of inflammation and APP in sIBM: IL-1beta induces accumulation of beta-amyloid in skeletal muscle. Brain 131 (2008): 1228-1240. [Pubmed]

M.P. Matheu, C. Beeton, A. Garcia, V. Chi, S. Rangaraju, O. Safrina, K. Monaghan, M.I. Uemura, D. Li, S. Pal, L.M. de la Maza, E. Monuki, A. Flügel, M.W. Pennington, I. Parker, K.G. Chandy, M.D. Cahalan. In situ imaging of effector/memory T cells during DTH and suppression by Kv1.3 channel block. Immunity 29 (2008): 602-14. [Pubmed]

N. Müller, J. van den Brandt, F. Odoardi, D. Tischner, J. Herath, A. Flügel, H.M. Reichardt. CD28 superagonistic antibodies elicit two functionally distinct waves of T cell activation. Journal of Clinical Investigation 118(2008):1405-1416. [Pubmed]

R. Linker, N. Kruse, S. Israel, T. Wei, S. Seubert, A. Hombach, B. Holtmann, F. Lühder, R. M. Ransohoff, M. Sendtner, R. Gold. LIF-deficiency modulates the immune response and limits autoimmune demyelination: a new role for neurotrophic cytokines in neuroinflammation. Journal of Immunology. 180 (2008), 2204-13. [Pubmed]

G.E. Rooney, C. Moran, S.S. McMahon, T. Ritter, M. Maenz, A. Flügel, P. Dockery, T. O’ Brien, L. Howard, A.J. Windebank, and F.B. Barry. Gene-Modified Mesenchymal Stem Cells Express Functionally Active Nerve Growth Factor on an Engineered Poly Lactic Glycolic Acid (PLGA) Substrate. Tissue Engineering Part A, 14 (2008):681-90. [Pubmed]

R. Linker, C. Weller, F. Lühder, A. Mohr, J. Schmidt, M. Knauth, J.M. Metselaar, R. Gold. Liposomal glucocorticoids in treatment of chronic autoimmune demyelination: Long-term protective effects and enhanced efficacy of methylprednisolone formulations. Experimental Neurology 211 (2008), 397-406. [Pubmed]

S. Wüst, J.v.d. Brandt, D. Tischner, A. Kleiman, J. P. Tuckermann, R. Gold, F Lühder, H. M. Reichardt. Peripheral T cells are the therapeutic targets of glucocorticoids in experimental autoimmune encephalomyelitis. Journal of Immunology 180 (2008), 8434-8443. [Pubmed]

R.A. Linker, F. Lühder, K.J. Kallen, D.H. Lee, B. Engelhardt, S. Rose-John, R. Gold. IL-6 transsignalling modulates the early effector phase of EAE and targets the bloo-brain-barrier. Journal of Neuroimmunology. 205 (2008), 64-72. [Pubmed]

 

2009

F. Lühder, D.H. Lee, R. Gold, J. Stegbauer, R.A. Linker. Small but powerful: Short peptide hormones and their role in autoimmune inflammation. Journal of Neuroimmunology 217 (2009), 1-7. [Pubmed]

S. Wüst, D. Tischner, M. John, J.P. Tuckermann, C. Menzfeld, U.K. Hanisch, J. van den Brandt, F. Lühder and H.M. Reichardt. Therapeutic and adverse effects of a non-steroidal glucocorticoid receptor ligand in a mouse model of Multiple Sclerosis. PLoS ONE (2009) 4(12): e8202. [Pubmed]

I.E. Muth, K. Barthel, M. Bähr, M.C. Dalakas, J. Schmidt. Pro-inflammatory cell stress in sIBM muscle: overexpression of αB-crystallin is associated with amyloid precursor protein and accumulation of β-amyloid. Journal of Neurology, Neurosurgery & Psychiatry 80 (2009): 1344-1349. [Pubmed]

I. Bartholomäus, N. Kawakami, F. Odoardi, C. Schläger, D. Miljkovic, J.W. Ellwart, W.E. Klinkert, T.B. Issekutz, C. Flügel-Koch, H. Wekerle, A. Flügel. Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions. Nature 462 (2009):94-8. [Pubmed]

G.E. Rooney, S.S. McMahon, T. Ritter, Y. Garcia, C. Moran, N.N. Madigan, A. Flügel, P. Dockery, T. O’Brien, L. Howard, A.J. Windebank, F.P. Barry. Glial-Derived Neurotrophic Factor-Expressing Mesenchymal Stem Cells Survive Transplantation Into the Contused Spinal Cord Without Differentiating Into Neural Cells. Tissue Engineering 15 (2009): 3049-59. [Pubmed]

D. Tischner, J. van den Brandt, A. Weishaupt , F. Lühder , M. J. Herold , and H. M. Reichardt. Stable silencing of the glucocorticoid receptor in myelin-specific T effector cells by retroviral delivery of shRNAs: insight into neuroinflammatory disease. European Journal of Immunology. 39 (2009), 2361-70. [Pubmed]

S. Cotte, N. von Ahsen, N. Kruse, B. Huber, A. Winkelmann, U. K. Zettl, M. Starck, N. König, N. Tellez, J. Dörr, F. Paul, F. Zipp, F. Lühder, H. Koepsell, H. Pannek, X. Montalban, R. Gold, and A. Chan. ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis. Brain 132 (2009), 2517-30. [Pubmed]

T. Kichberger, C. Moreau, G.K. Wagner, R. Fliegert, C.C. Siebrands, M. Nebel, F. Schmid, A. Harneit, F. Odoardi, A. Flügel, B.V.L. Potter, A.H. Guse. 8-Bromo-cyclic inosine diphosphoribose: towards a selective cyclic ADP-ribose agonist. Biochemical Journal, 422 (2009):139-49. [Pubmed]

W. Dammermann+, B. Zhang+, M. Nebel+, C. Cordiglieri+, F. Odoardi, T. Kirchberger, N. Kawakami, J. Dowden, F. Schmid, K. Dornmair, M. Hohenegger, A. Flügel*, A.H. Guse*, B.V.L. Potter* NAADP mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist, Proceedings of the National Academy of Sciences of the United States of America 106 (2009):10678-83. [Pubmed]

M.C. Dalakas, G. Rakocevic, J. Schmidt, M. Salajegheh, B. McElroy, M.O. Harris-Love, J.A. Shrader, J.A.E. Levy, J. Dambrosia, R.L. Kampen, D.A. Bruno, A.D. Kirk. Effect of Alemtuzumab (Campath 1-H) in patients with Inclusion Body Myositis. Brain 132 (2009): 1536-1544. [Pubmed]

F. Lühderand H. Reichardt.Traditional concepts and future avenues of glucocorticoid action in experimental autoimmune encephalomyelitis and multiple sclerosis therapy. Critical Reviews in Immunology 29 (2009), 255-73. [Pubmed]

J. Schmidt.[Pathogenesis of sporadic Inclusion Body Myositis: Significance of Inflammation and Implications for Therapeutic Strategies.] Aktuelle Neurologie 36 (2009): 121-125.

R.A. Linker, R. Gold, F. Lühder. Function of neurotrophic factors beyond the nervous system: Inflammation and autoimmune demyelination. Critical Reviews in Immunology 29 (2009), 43-68. [Pubmed]

T. Gogishvili, D. Langenhorst, F. Lühder, F. Elias, K. Elflein, K.M. Dennehy, R. Gold, T. Hünig. Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice. PLoS ONE. (2009); 4(2):e4643. [Pubmed]

 

2010

Bartl J, Link P, Schlosser C, Gerlach M, Schmitt A, Walitza S, Riederer P, Grünblatt E. Effects of methylphenidate: the cellular point of view. Atten Def Hyp Disord 2 (2010): 225-232. [Pubmed]

R.A. Linker, D.-H. Lee, S. Demir, S. Wiese, N. Kruse, I. Siglienti, E. Gerhardt, H. Neumann, M. Sendtner, F. Lühder, R. Gold. Functional role of brain-derived neurotrophic factor in neuroprotective autommunity: therapeutic implications in a model of multiple sclerosis. Brain 133 (2010): 2248-2263. [Pubmed]

Z. Shevtsova, M. Garrido, J. Weishaupt, P. Saftig, M. Bähr, F. Lühder, S. Kügler. CNS-expressed cathepsin D prevents lymphopenia in a murine model of congenital neuronal ceroid lipofuscinosis. Am J Pathol 177 (2010): 271-9. [Pubmed]

T. Hünig, F. Lühder, K. Elflein, T. Gogishvili, M. Fröhlich, R. Guler, A. Cutler, F. Brombacher. CD28 and IL-4: two heavyweights controlling the balance between immunity and inflammation. Med Microbiol Immunol 199 (2010): 239-46. [Pubmed]

I. Volovitz, Y. Marmor, F. Mora, A. Flügel, F. Odoardi, L. Eisenbach, I.R. Cohen. T cell vaccination induces the elimination of EAE effector T cells: analysis using GFP-transduced, encephalitogenic T cells. J. Autoimmunity (2010) Sep; 35(2): 135-44. Epub 2010 Jun 26. [Pubmed]

C. Cordiglieri, F. Odoardi, B. Zhang, M. Nebel, N. Kawakami, W.E.F. Klinkert, D. Lodygin, F. Lühder, E. Breunig, D. Schild, V. Kumar, K. Dornmair, W. Dammermann; B.V.L. Potter, A.H. Guse, A. Flügel. NAADP-mediated Ca2+ signaling in effector T cells regulates autoimmunity of the nervous system, Brain 133 (2010): 1930-43. [Pubmed]

N. Kawakami, A. Flügel. Knocking at the brain’s door: intravital two-photon imaging of autoreactive T cell interactions with CNS structures. Seminars in Immunopathology (2010) Sep; 32(3): 275-87. [Pubmed]